This deposition contains raw diffraction images collected at LCLS-MFX for the following paper: "Conformational flexibility of soybean lipoxygenase is coupled to crystal solvent content in serial crystallography" doi: https://doi.org/10.64898/2026.05.30.729005 Datasets This deposition contains the following datasets mentioned in the paper: * Soybean Lipoxygenase 1 (SLO-1) - Small Cell (PDB ID = 9o4s) - Large Cell (PDB ID = 9o4t) Geometry / Calibration * DIALS geometry file * LCLS calib folder associated with MFXL1013721 The Rayonix RAYONIX MX340-HS is a single panel CCD that was run in 4X4 binning mode, resulting in images that are 1,920 X 1,920 pixels. The included detector geometry file for cctbx.xfel (DIALS) was used to process all runs, though rerefining geometry after initial indexing could be valuable. It's worth noting that both datasets are spread across the runs. The two polymorphs are present throughout, and have to be separated per the methods in the associated publication. A sample change occurs between run 284 and 285, expect the ratio of polymorphs shift.